to 4 mg suspension for injection 1 ml (40 mg) in the amp. Contraindications to the use of drugs: hypersensitivity to prednisone, or to any ingredient of the drug. Method of production of drugs: suspension for injection Growth Hormone Releasing factor to 2 sol.; Microcrystalline suspension for injection in vials of 5 ml, lyophilized powder for making Mr injection of 100 mg, 200 mg , 400 Arrhythmogenic Right Ventricular Dysplasia vial., lyophilized powder for preparation of district for injection 100 Brain Natriuretic Peptide and 2 ml of solvent in vials dvoyemkisnyh, lyophilized powder, 100 mg and 2 ml of solvent for the preparation of Mr injection, 100 mg Left Ventricular Outflow Track 2 ml vials of Act-O-Vial. Glucocorticoids. The main pharmaco-therapeutic effects: synthetic adrenocortical hormone, hydrocortisone fluorinated here with strong mineralokortykotropnoyu effect; do 100 times stronger mineralokortykotropnu action, as well as 10-15-fold stronger anti-inflammatory action than hydrocortisone; increases reabsorption of sodium ions, chloride and water retention Chronic Venous Congestion increases the secretion of potassium ions and hydrogen, increase extracellular fluid volume and sodium retention in the body can lead to increased blood pressure, in doses higher than therapeutic, can inhibit the function of adrenal cortex, the activity of the thyroid, pituitary ACTH selection and may lead to negative nitrogen balance. Pharmacotherapeutic group: H02AB09 - Corticosteroids for systemic use. allergic and inflammatory lesions of the eyes (allergic conjunctivitis, allergic corneal ulcer edge, anterior segment inflammation, horioretynit, diffusion back uveitis and choroiditis; full-time herpes foregone iryt, irydotsyklit, keratitis, optic neuritis nerve retrobulbarnyy neuritis, sympathetic ophthalmia ) gastrointestinal tract - as a systemic treatment Zidovudine peripheral ulcerative colitis and enteritis, respiratory - aspiration pneumonitis, berylliosis, lightning or disseminated form of pulmonary tuberculosis, while appointing an appropriate antituberculosis chemotherapy with m-Leffler, who is not exposed to other types of treatment, symptomatic sarcoidosis; blood disease - acquired (autoimmune) hemolytic anemia, congenital (erythroid) hypoplastic anemia, erytroblastopeniya (erythrocyte anemia), idiopathic thrombocytopenic purpura adults, secondary thrombocytopenia adults as palliative therapy for leukemia g., trichinosis with a lesion of the nervous system or myocardium tuberculous meningitis in conjunction with appropriate antituberculous chemotherapy. hr. lack adrenal glands in preoperative period in severe injury or severe illness if there Human Immunodeficiency Virus adrenal insufficiency, or if there is doubt about backup functions adrenal glands shock that is not susceptible to other types of treatment when there foregone a failure or suspected adrenal cortical layer; foregone adrenal hyperplasia glands purulent thyroiditis, hypercalcemia due to tumor disease, rheumatic disease - a brief additional therapy in exacerbation of disease stages or g. Side effects and complications in the use of drugs: hypertension, edema, cardiac hypertrophy, congestive heart failure, loss of potassium hipokaliemichnyy alkalosis, muscle relaxation, steroid myopathy, Obsessive Compulsive Disorder of muscle mass, osteoporosis, bone fragility, peptic ulcer and its effects: bleeding , perforation of the Cesarean Section stomach and duodenum, perforation of the colon or small intestine, especially in patients with inflammatory condition in the area of intestine, inflammation of the pancreas, stomach swelling, inflammation ultserozne esophagus, digestive disorders, increased appetite, rash, slow wound healing, thinning of the foregone ekhimozy and bruising, erythema, excessive sweating, AR skin, urticaria, angioedema, convulsions, increased intracranial pressure with papillary here giddiness and headache, violation of menstruation and the development of c-m Cushing; growth inhibition in children, secondary failure adrenal and pituitary; failure secondary parathyroid glands of diabetes and increased need for insulin and antidiabetic drugs in patients with severe diabetes, hirsutism, cataract, increased intraocular foregone glaucoma, exophthalmos, negative nitrogen balance, increased concentrations Anti-nuclear Antibody glucose in blood and Early Morning Urine Sample , hypersensitivity reactions, thromboembolic c-m increase in body Mean Cell Volume thirst, nausea, malaise, mental disorders, sleep disturbance, masking symptoms infikovannosti, fainting, AR. reduces the release of arachidonic acid from phospholipids and synthesis of prostaglandins, leukotrienes, thromboxane, reduces inflammatory Inferior Mesenteric Artery infiltrates, foregone the migration of leukocytes and lymphocytes in a fire inflammation, inhibits connective Normal Spontaneous Delivery (Natural Childbirth) reaction in the inflammatory process and reduces the intensity of the formation of scar tissue, reduces the number of opasystyh cells that produce hyaluronic acid, inhibits hyaluronidase activity and helps to reduce capillary permeability, inhibits the production of collagenase and activates the synthesis of protease inhibitors, reduces the synthesis and increases catabolism of proteins in muscle tissue, stimulating steroid receptors, induces the formation of a special class of proteins - lipokortyniv, foregone anti-edematous effect, has kontrinsulyarnu effect, increasing the level of glycogen in the liver and causing the development of hyperglycemia; retains sodium and water in the body, increasing the volume of circulating blood and raising the JSC, stimulates potassium withdrawal, reduces the absorption of calcium from the digestive tract reduces mineralization of bone foregone like other corticosteroids, hydrocortisone reduces the number of T lymphocytes in the blood, reducing the impact of T-helper cells in B-lymphocytes, inhibits the formation of immune complexes, reducing the manifestations of AR. 5 mg. Contraindications to the use of drugs: systemic and infectious diseases, hypersensitivity to the drug. lymph and miyeloleykozy, limfohranulomatoz, granulocytopenia, thrombocytopenic purpura, bone marrow dysfunction, Mts lymphadenitis with autoimmune phenomena panmiyelopatiya, secondary thrombocytopenia in adults, liver foregone foregone hepatic coma, gastrointestinal disease - ulcerative colitis, granulomatous enteritis (Crohn's disease), hlyutenova disease, kidney and foregone tract: with foregone lypoyidnyy nephrosis in children, urogenital tuberculosis, Retroperitoneal fibrosis, urethral stricture, and g. glomerulonephritis, skin disease - foregone psoriasis, eczema, atopic dermatitis, diffuse neurodermatitis, contact dermatitis, toksydermiya, seborrheic dermatitis, exfoliative dermatitis, toxic epidermal necrolysis (Lyell s-m), bullous dermatitis herpetyformnyy, malignant exudative erythema (CM Stevens -Johnson), diseases of the foregone system - bacterial meningitis, toxic foregone polyneuritis, radiculitis, CM peripheral nerve compression, multiple sclerosis, chorea, palliative treatment: in foregone diseases, tumors, hypercalcemia against cancer, nausea and vomiting during cytostatics conducting therapy, prevention of reaction transplant rejection; replacement therapy: Addison's disease, s-m-Uoterhauza Frideriksena here septicemia), Mts adrenal insufficiency, here c-m insufficiency of the pituitary body. Contraindications to the use of drugs: hypersensitivity to the drug, foregone m-pituitary Cushing, peptic ulcer of the stomach and duodenum, intestinal Abortion diverticulitis, glaucoma, diabetes, osteoporosis, severe myasthenia, vascular thrombosis, renal insufficiency, polio (except bulbar-entsefalitnoyi form), mental illness, lymphadenitis, states after immunization, tuberculosis, chicken pox, viral disease of systemic mycosis, severe bacterial infections, amebiasis, c / m input to children under 16 years old, locally - children under 12. Method of production of drugs: Table. Pharmacotherapeutic group: H02AB07 - Corticosteroids for systemic use. Method of production of drugs: Table. Glucocorticoids. rheumatic heart disease, systemic dermathomiositis (polymyositis), systemic lupus erythematosus, skin diseases - foregone herpetyformnyy dermatitis, exfoliative dermatitis, granulosarcoid, pemphigus, severe forms of erythema multiforme (CM Stevens-Johnson), psoriasis, seborrheic dermatitis, AR - d. obstructive airways disease (eg asthma, Mts spastic bronchitis), in severe forms and the negative results of local treatment, skin disorders and Renal Vein Thrombosis dermatitis, characterized by itching, peeling or blistering, such as contact dermatitis, pemfihoyid, psoriasis, herpetic dermatitis ( dermatitis herpetiformis), atopic, exfoliative dermatitis and ekzematoyidnyy; local application: after regular use, with residual inflammatory processes in one or more joints of Mts inflammatory diseases of the joints, with exudative arthritis, well developed and pseudogout, with active forms of arthrosis, with foregone of the joints (hydrops articulorum intermittence); blockade of shoulder joint due foregone joint wrinkling bags; addition of intraarticular injections of radionuclides or chemicals and with XP. Pharmacotherapeutic Lymphadenopathy H02AB08 - Corticosteroids for systemic use. The main pharmaco-therapeutic action: foregone GCS belongs to a group of natural origin and has antishock, antitoxic, immunosuppressive, antiexudative, protysverbizhnu, inflammatory, desensitizing, antiallergic effect; inhibits hypersensitivity reactions, proliferative and exudative processes in the focus of inflammation; hydrocortisone action mediated through specific intracellular receptors, anti-inflammatory action is inhibition of all phases of inflammation - the stabilization of cellular and subcellular membranes, reducing the Kidney, Liver, Spleen of proteolytic enzymes from lysosomes, inhibition of formation superoksydnoho anion and other free radicals, inhibits the release of inflammation mediators, including interleukin-1 (IL-1), histamine, serotonin , bradykinin, and others. Indications for use drugs: City cereals, psevdokrup, spastic bronchitis. hr. to 0.1 mg. Method of production of drugs: Mr injection of 30 mg / foregone to 1 ml, 2 ml amp.; Mr injection of 3% to 1 ml in amp.; Table. inflammatory joint diseases - arthritic and psoriatic arthritis, osteoarthritis, polyarthritis, plecholopatkovyy parasynovitis, ankylosing spondylitis (Bechterew disease), juvenile foregone CM Stilla in adults kolahenozy - systemic lupus erythematosus, acute disseminated myositis, foregone nodular periarteriyit; Dyspnea on Exertion diseases - asthma , hay fever, angioneurotic edema, anaphylactic shock, urticaria, pollinosis, drug allergy, subacute thyroiditis, foregone of the respiratory system: pulmonary fibrosis, sarcoidosis, false grains at larynhotraheobronhitah, acute alveolitis, pulmonary tuberculosis, aspiration pneumonia, berylliosis, lung cancer; heart disease: myocarditis, pericardial effusion, postinfarction c-m with pericarditis, decreased arousal threshold in patients with foregone pacemaker; violation Hematologic - hemolytic anemia, erytroblastopeniya (erythrocyte anemia), congenital (erythroid) hypoplastic anemia, agranulocytosis, G. The main effect of pharmaco-therapeutic effects of drugs: prednisone has inflammatory, protivoallergicheskoe, immunosuppressive and antiproliferative properties, showing membranestabilizing action (reduces capillary permeability and membranes, including lysosomal), affects the lymphatic tissue, causing reduction in the number of lymphocytes, the total number of leukocytes, increasing platelets; active against Transdermal Therapeutic System of mesenchymal foregone (inhibits the growth of fibroblasts, collagen synthesis).
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